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why does glp 1 increase heart rate GLP-1 Genetics: How Genes Affect Appetite, Semaglutide, and Tirzepatide Response

Marsoni M251S
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4.2 ★★★★★
Based on 952 reviews
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K
Verified Purchase
Kathy
Battle Creek, US
★★★★★ 5
Works well, tough
Held the bully stick firmly for my crazy aggressive pit bull lab mix. It's very heavy though. When she starts throwing it around you can really hear it. She also hasn't destroyed it. Worth the money.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 13, 2026
K
Verified Purchase
Kim
Bozeman, US
★★★★★ 5
Great gadget!
This little gadget is a lifesaver! Holds bully sticks perfectly! Buy it! My pup enjoys using it and is easy to hold.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 11, 2026
A
Verified Purchase
Alibill
Cuba, US
★★★★★ 5
It absolutely holds a bully or collagen sticks in place!
This actually works! I was skeptical that it could hold a treat but it does hold my Aussies collagen sticks in place so he doesn’t just try to swallow them. It is pretty heavy too.
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Reviewed in the United States on October 21, 2025
R
R. Reviews
Bozeman, US
★★★★★ 4
Solid Build, But Not German Shepherd-Proof
I bought this bully stick holder for my German Shepherd, who is an aggressive chewer and has a talent for demolishing toys in minutes. The design is sturdy, and the material feels genuinely heavy-duty — no issues with cracks or breakage so far. However, the biggest problem I’ve run into is that the bully stick doesn’t always stay securely in place. My dog is strong and smart, and within a few minutes, he can twist or yank the stick loose and start chomping on the whole thing, which defeats the safety purpose. I’ve tried adjusting how I insert the stick, but it doesn’t always hold firm, especially with thinner bully sticks. That said, it does work better with thicker, straight sticks, so I’d recommend it if your pup isn’t quite as determined (or stubborn!) as mine. I still use it under supervision, and it slows him down a bit, but I was hoping for a more secure grip. Great idea and solid quality — just wish it was more GSD-proof.
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Reviewed in the United States on July 13, 2025
R
Verified Purchase
Rita Cooper
Massapequa, US
★★★★★ 5
Totally worth the money!
Love this product! It hold the bully sticks very well!! And it can be a toy!
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Reviewed in the United States on August 28, 2025

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