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semaglutide and bone loss I kept seeing patients on semaglutide and tirzepatide and asking myself: what is this much weight loss doing to their skeleton? Turns out the research is more unsettling than most people realize

Marsoni M251S
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4.8 ★★★★★
Based on 1592 reviews
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A
Verified Purchase
Amazon Customer
Charlottesville, US
★★★★★ 3
Ehh
Size: Medium, Color: Multicoloured E-(5-pack)
Very thin, still comfy but very thin material. Super soft though. I've worn and washed and they have held up but I won't be repurchasing bc these are so thin
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 14, 2026
G
Verified Purchase
Grma4m&m
Lexington, US
★★★★★ 5
They’re fantastic!!!!
Size: X-Large, Color: Multicoloured E-(5-pack)
My clothing size is 16/18 and XL. Even though Amazon suggested a size XXL, I ordered my normal XL and they fit perfectly. The fabric for this style is 92% bamboo viscose and is amazingly soft and almost silky feeling. I had ordered a different boy short in this brand but they were 80% bamboo viscose and the fabric was significantly heavier. I returned those and ordered these.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 25, 2026
S
Verified Purchase
Siobhan Smith
Waukegan, US
★★★★★ 5
Super soft and comfortable!
I haven't bought new underwear in forever. I used to wear thongs, but now find them incredibly uncomfortable. The last few times I've tried to buy new underwear, the sizing was either way off (I'm a medium, but gave up after having to return them for a large and then extra large) or the quality was horrible (two brands stretch waaaay out and they can fall down while wearing them (I have larger ass-ets, so they shouldn't start to slide down during use). I tried these after buying some bamboo pyjamas and I love them! They are incredibly soft, comfortable, and stretchy. I can use them all day, and they work well, whether I'm lounging on the couch or wearing them under my spandex shorts at the gym, they don't ride up or slide down. They are both comfortable and look sexy, while providing support in all the right places. I haven't had them too long, so I can't speak on the durability, but they appear to be of good quality and I plan to order more, this time without the band.
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Reviewed in the United States on November 13, 2025
M
Verified Purchase
Mariel
Grantham, US
★★★★★ 5
Well made, light fabric. Waist doesn't roll.
These bamboo underwear really do keep you cool. They fit true to size, and wear easily. the wide elastic waist band doesn't roll on me. They are comfortable to wear, washed and dried easily. The material has some stretch to it, but not a lot. Well made, no stray strings. Perfect fit for me. Just what I was looking for.
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Reviewed in the United States on May 17, 2026
F
Verified Purchase
Finngirl
Fort Morgan, US
★★★★★ 5
Good quality, smooth feel
I got these briefs so recently that have washed just one pair so far. First off, these are very comfortable, the material is soft & bordering silky, good quality sewing. Wash well and minimal if any shrinkage. They do come a bit wrinkled from the dryer but hey, these are underwear and will go on smoothly. If it were a t-shirt, I would look sloppy. I feel the sizing is accurate. No rolling and these don't announce themselves under clothing. Planning on getting more of these boxers and replacing my old panties.
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Reviewed in the United States on January 31, 2026

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