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Research shows that weight often returns after stopping GLP-1 drugs like Ozempic and Wegovy. In the STEP-1 Extension Trial (published in Diabetes, Obesity and Metabolism), participants regained about two-thirds of the weight
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Trajectory of the body weight after drug discontinuation in the treatment of anti-obesity medications | BMC Medicine
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What are GLP-1s?
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Two Years After Stopping GLP-1s, Most Patients Sustain at Least Some Weight Loss
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Those discontinuing GLP-1 medications rapidly regained weight
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Key Facts GPs Should Know About GLP-1 Analogs
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Weight regain after stopping GLP-1 medications can feel frustrating and emotionally exhausting for many people. This is not always about “lack of discipline” or motivation. After weight loss, the body may respond
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