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does semaglutide lose efficacy over time Pretty interesting result from new weight loss drug semaglutide. Effective until you stop taking it : r/biotech

Marsoni M251S
Sale price$28.12
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4.1 ★★★★★
Based on 103 reviews
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Product Reviews
L
Verified Purchase
Larry Z.
Belleville, US
★★★★★ 5
My dog loves this ball
Color: Green
The battery on this lasts forever. The random on/off motion and when it gets touched inducing motion just keeps my dog guessing and occupied for a long time. My dog's tail is wagging the whole time.
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Reviewed in the United States on May 5, 2026
D
Verified Purchase
DM
Cuba, US
★★★★★ 5
Great ball
I have bought two of these in different colors. My Yorkie loves them. They’re very interactive even if you don’t put the cover on it they move and if he’s not playing with it, it tends to go into sleep mode.My Yorkie got the cover off the ball within the first two minutes. But he loves the ball. Now bought 2nd ball. The ones with covers don’t work he rips the covers off.
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Reviewed in the United States on October 15, 2025
L
Verified Purchase
Lindsey Newhouse
Lowell, US
★★★★★ 5
Super Fun
Color: Green
One of the most entertaining things you could buy. The dogs go crazy over it and have so much fun. It's a bit loud on hard floors, but honestly worth it for the laughs. Seems pretty durable too. I have 2 labs; one started out uninterested and the other started off scared of it, but not too long after, they both started going crazy, tossing and carrying it around while it shook.
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Reviewed in the United States on March 21, 2026
M
Verified Purchase
Monica
Massapequa, US
★★★★★ 4
Great customer service
Bought this for our dog for Christmas! He loved it! It sadly stopped working shortly after. Recently emailed the product site themselves and they sent a new one that week! Great customer service and great toy!!
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Reviewed in the United States on February 25, 2026
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Verified Purchase
J. Rogers
Dallas, US
★★★★★ 5
This is a great ball for high energy dogs.
Color: Blue
I have a Belgian Malinois, so you can imagine the Maligator jaws. Just opened this today and let her play with it indoors. She LOVES IT. It wore her out and it’s a toy she can really stay focused on without needing me to throw or roll for her. It moves on its own! I supervised her play. I was hoping it was too big to get under the couch, but no. It goes right under it. I had to block off the gap so I didn’t have to keep getting it out from under for her. The outter “shell” is very durable! When she had resting moments, she chewed it pretty good - I could hear the material squeaking against her teeth. I was worried she was tearing it up, but nope! Not a mark on it. It’s easy to set up and operate. It needed charging before play. After hours of play, she was able to somehow unscrew the outter shell. This concerned me bc the smaller, inner ball mechanism came out but I saw it right away and was able to put it back together. So, make sure it’s screwed together tightly (which I thought I had done without breaking it) and check it from time to time to make sure it hasn’t loosened. This is a great ball for her incredible high energy drive. It gives her the work and fun play she needs to get tired, which I love. This toy is on the expensive end, but so far it’s worth it. Now we’ll see how long it lasts!
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Reviewed in the United States on October 7, 2025

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