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A first-in-human study suggested that tirzepatide — a dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist — modulated abnormal activity in the brain's nucleus accumbens, thereby reducing food cravings and inducing
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Dual GLP-1 and GIP Agonist Tirzepatide Exerted Neuroprotective Action in a Parkinson's Disease Rat Model
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Tirzepatide shows neuroprotective effects via regulating brain glucose metabolism in APP/PS1 mice
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