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Glucose dependent insulinotropic polypeptide receptor signaling in oligodendrocytes increases the weight loss action of GLP 1R agonism: Cell Metabolism Burn30 GLP 1 Support Metabolic Weight Loss Formula Bodybuilding.com Science Behind GLP 1 GIP and Glucagon Receptor Agonists for Obesity Research News & Announcements Cayman Chemical What Are GLP 1 Medications? A Weight Loss Doctor Weighs In BistroMD As GLP 1 medicines evolve to target more receptors beyond the GLP 1R, ideally exhibiting enhanced efficacy, new questions arise about long term safety. Mechanistic and outcome studies will help define the value proposition GLP 1
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★★★★★ 4
Helps my moisturizer absorb better
Color: Cyano Pink Spicule
I’m not quite sure if the product is fully working the way it is supposed to but I do like that when I use this and the apply moisturizer, it absorbs into my skin better and leaves my skin smoother and a lot less greasy. It’s easy to throw in my travel bag because of the size and you really only just need a little for each use so it goes a long way got the cost.
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Reviewed in the United States on May 31, 2026
★★★★★ 5
Amazing!
Color: Cyano Pink Spicule
This makes my skin feel so smooth. The appearance of my skin also is starting to look a lot better/younger. I've been using it for a week and a half already seeing changes.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 11, 2026
★★★★★ 3
Brightens, doesn't firm
Color: Cyano Pink Spicule
I've been using this for about a month now, every night on my face and neck, hoping to reduce the appearance of wrinkles and tighten some of my skin in that area that seems to be losing elasticity. On my neck, I've honestly noticed no real difference in 4 weeks of continued, consistent daily use. The skin on my face does seem brighter and somewhat less textured than before, but I haven't noticed any change in the issues I was hoping this would resolve, based on the claims and how it was marketed. So... not a bad addition to my skincare, but not the solution I was looking for.
Some have expressed concerns about it tingling or stinging... You can feel something when you apply it, it's almost like the feeling of static electricity, but it's very mild. I wouldn't let that stop you from giving it a try if you were concerned about it. It didn't cause my sensitive skin any breakouts or redness (although I was applying it at night before bed, so perhaps any redness was calmed overnight). I'm going to go ahead and finish the bottle, but based on these results, I probably won't repurchase.
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Reviewed in the United States on May 3, 2026
★★★★★ 4
Decent Product
Color: Cyano Pink Spicule
Not bad for the $ , it makes my skin feel good.
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Reviewed in the United States on May 24, 2026
★★★★★ 5
Helped Tighten My Skin & Minimize Pores
Color: Cyano Pink Spicule, Color: Cyano Pink Spicule
I’ve loved the Dr. Melaxin Cyano Pink Spicule Serum! The bottle is small, but it lasted me around 6 months since I only use one pump every other night. When I first started using it, I noticed a tingling sensation, but over time my skin adjusted and I barely notice it now. I’ve definitely seen my pores appear smaller and my skin feels tighter and smoother after using it.
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