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Reviewed in the United States on August 10, 2025
surmount-1 tirzepatide obesity nejm 2022 weight loss percent STEP 1 (NEJM 2021) showed that semaglutide 2.4 mg once weekly produced a mean weight loss of 14.9% in 1,961 adults with obesity — with 1 in 3 participants losing over 20%
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